منابع مشابه
Teaching NeuroImages: Neuroradiologic evolution of Leigh disease
A 2-year-old girl with no significant family history presented with motor developmental delay and strabismus. MRI revealed unilateral basal ganglia and brainstem lesions (figure 1). Eighteen months later, she developed acute onset right arm weakness, leading to a diagnosis of multiphasic disseminated encephalomyelitis. Treatment with steroids and mycophenolate produced no symptomatic or imaging...
متن کاملChildhood moyamoya disease accompanying Leigh syndrome.
Moyamoya disease is a cerebrovasculopathy of unknown etiology during the course of which the main and terminal veins of the internal carotid artery undergo progressive vein occlusion. Leigh syndrome is a mitochondrial encephalomyopathy that occurs due to "cytochrome c oxidase deficiency" characterized by psychomotor retardation, difficulty in eating, seizures, hypotonia, respiratory disorders a...
متن کاملSubacute necrotising encephalomyelopathy (Leigh’s disease; Leigh syndrome)
Like so many complex and incurable neurological disorders, the disease first described in this journal in 1951 by (Archibald) Denis Leigh (1915–1998; figure 1) as ‘Subacute Necrotising Encephalomyelopathy’ (SNE) remained for many years a rare and intriguing enigma, of interest mainly to paediatric neurologists and neuropathologists. The more recent history of this disorder, now designated Leigh...
متن کاملLeigh Stewart
When I tell people that I am a mathematics major and a studio art minor, overwhelmingly the response I get is one of surprise that I have chosen such a strange combination of disciplines. “They’re so different from each other!” people exclaim. Mathematics is often considered a “left-brained” discipline, logical and linear in its structure, and art a “rightbrained” activity, stirring one’s intui...
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ژورنال
عنوان ژورنال: Medical Hypotheses
سال: 2017
ISSN: 0306-9877
DOI: 10.1016/j.mehy.2017.01.016